"Scent of a Woman" is a romantic-melodrama that depicts the life of a 30'ish woman who works as a low-level clerk. She works hard, but lives her life without much joy. She then learns that she is dying. The woman decides to travel aboard to find happiness ... Lee Yeon-Jae (Kim Sun-A) works at travel agency Line Tour as an under-appreciated assistant. She's often belittled, sexually harassed, & tasked to do menial jobs by her boss, but she never stands up for herself, fearing for her job. Lee Yeon-Jae supports her mother and without her job, believes she won't be able to get married. One day, because of a car accident, Lee Yeon-Jae goes to the hospital. There she meets Dr. Chae Eun-Suk (Uhm Ki-Joon). As children, Yeon-Jae and Eun-Suk were friends, but Eun-Suk now acts as if he does not know her. Dr. Eun-Suk informs Yeon-Jae that she has a tumor and needs another examination. Yeon-Jae goes back to the company and asks for a day off to get the medical examination. Instead of getting the day off, Yeon-Jae is assigned to be a guide for high profile client Andy Wilson.